Cheapest GLP-1 Without Insurance Online: Legit Options & Prices (2026)

Cheapest GLP-1 Without Insurance - Affordable Health Solutions, Transparent Pricing
By WPG Research TeamUpdated January 9, 2026Pricing verified January 9, 2026

Affiliate Disclosure: We earn commissions when you sign up through our links. This doesn't affect our rankings. Learn more·For informational purposes only—not medical advice.

Quick Answer (Start Here)

If you're searching "cheapest GLP-1 without insurance," you're usually in one of two situations: insurance said no, or the $1,000+/month retail price made GLP-1s feel impossible. This page helps you choose a legit option fast—without getting scammed or blindsided by hidden fees.

Cheapest FDA-approved GLP-1 (self-pay):

Wegovy® tablets: $149/mo for 1.5 mg and 4 mg (4 mg offer through April 15, 2026, then $199/mo). Higher doses at $299/mo via NovoCare.

Cheapest FDA-approved injection (cash pay):

Zepbound® vials: $299/mo (2.5 mg), $399/mo (5 mg), $449/mo (7.5–15 mg if refill within 45 days).

Cheapest clearly-published online program (compounded):

Tuyo Health: $155/mo, no membership fees, labs included (per their page).

Important reality check:

Compounded GLP-1s are not FDA-approved as finished drugs. The FDA has reported dosing errors (including hospitalizations) with compounded injectable semaglutide and warns about salt forms (semaglutide sodium/acetate) which are different active ingredients than approved drugs.

BEST VALUEOur top pick for compounded GLP-1

Tuyo Health — $155/mo with Labs Included

The lowest published compounded semaglutide price we verified: $155/month with no membership fees, free shipping, and quarterly labs included. Ideal if you want maximum value with proper medical oversight.

  • Compounded semaglutide
  • Labs every 3 months
  • No membership fees
Start at $155/mo

Affiliate link. See disclosure below.

Quick Picks (If You Don't Want to Read Everything)

Your PriorityBest OptionPriceLink
Cheapest FDA-approved (no needles)Wegovy tablets$149/mo starterSee official pricing
Cheapest FDA-approved injectionZepbound vials$299/mo starterSee official pricing
Lowest published compounded price + labs includedTuyo HealthBEST VALUE$155/moStart at $155/mo with labs included
Simple pricing + all 50 states (per FAQ)Breeze MedsAll 50 States$199/moStart at $199/mo
Support + coaching includedEden HealthSupportFrom $119 first mo*See Eden pricing
Comprehensive onboarding + educationSkinnyRxBeginnersFrom $199/moSee SkinnyRx pricing
Lowest first month (injectable)MEDViLow Entry$179 first monthTry month 1 for $179

Note: Compounded medications are not FDA-approved products. All affiliate links are clearly marked. Always verify current pricing at checkout.

*Eden describes this as a first-month discount on a 3-month plan. Ongoing cost depends on plan selection—confirm your exact total at checkout.

Comparison Table: Cheapest GLP-1 Without Insurance (Online) — Verified January 9, 2026

Below is the full comparison. FDA-approved = brand medication made under FDA oversight. Compounded = prepared by a pharmacy for a patient-specific prescription; not FDA-approved as a finished product.

Option / ProviderTypeStarting PriceVerified
Wegovy® tablets (oral)FDA-approved$149/mo (1.5 mg; 4 mg for now)Jan 9, 2026
Wegovy® pen (injection)FDA-approved$199/mo intro offerJan 9, 2026
Zepbound® vials (cash pay)FDA-approved$299/mo (2.5 mg) · $399/mo (5 mg)Jan 9, 2026
Tuyo HealthBEST VALUECompounded$155/moJan 9, 2026
Breeze MedsCompoundedStarting at $199Jan 9, 2026
Eden HealthSupportCompoundedFrom $119 first mo*Jan 9, 2026
SkinnyRxBeginnersCompoundedFrom $199/moJan 9, 2026
MEDViLow EntryCompounded$179 first monthJan 9, 2026
What's Usually Included vs. Extra

Usually included:

  • • Clinician review + prescription
  • • Medication
  • • Standard shipping

Sometimes extra:

  • • Lab work (some include it, some don't)
  • • Supplies (syringes, alcohol swabs)
  • • Expedited shipping
  • • Follow-up visits or coaching

Always confirm what's included before you pay. Ask specifically about lab requirements.

Brand-Name Cash-Pay in 2026: What Changed

For years, "cheapest GLP-1 without insurance" basically meant compounded programs—because brand-name prices were usually out of reach. In 2026, that changed.

Wegovy® Tablets (Pill): The New Low-Friction Self-Pay Path

Wegovy's official cost page lists:

  • Self-pay pill starting at $149/month for the 1.5 mg dose
  • The 4 mg pill is listed at $149/month only until April 15, 2026, then $199/month
  • Higher pill doses (9 mg and 25 mg) are listed at $299/month through NovoCare® Pharmacy terms

Important: offers have eligibility rules and can change—always confirm the current offer terms before paying.

Wegovy® Pen (Injection): Official Self-Pay "Intro" Route

Wegovy's official pricing page lists a self-pay offer for the pen:

  • $199/month as a limited-time intro offer (for up to two monthly fills of the 0.25 mg or 0.5 mg doses)
  • $349/month thereafter (terms/eligibility apply)

This matters if you want injections but prefer Wegovy (semaglutide) over Zepbound (tirzepatide).

Zepbound® Vials: Why the 45-Day Refill Rule Matters

Zepbound's official savings page lists:

  • $299/month for 2.5 mg vials (2.5 mg is the starting dose and not approved as a maintenance dose)
  • $399/month for 5 mg vials
  • $449/month for 7.5–15 mg vials only if you refill within 45 days of your previous delivery/receipt date

Key point: If you refill after 45 days, the "regular price" tiers are much higher—so budget for your actual refill cadence.

Compounded GLP-1 Reality Check (2025–2026)

Compounded GLP-1 programs can be cheaper. But they're also the area where people get misled the most—especially when marketing makes them sound "identical" to FDA-approved drugs. Here are the facts you need to stay safe:

1) Compounded GLP-1s are not FDA-approved finished drugs

FDA notes that compounded drugs do not undergo FDA premarket review for safety, effectiveness, or quality. FDA also says compounded drugs generally should be used only when a patient's medical needs can't be met by an FDA-approved drug.

2) The FDA has documented real harms from dosing mistakes

FDA has received reports of adverse events (some requiring hospitalization) that may be related to overdoses due to dosing errors with compounded injectable semaglutide. Many errors come from:

  • • Confusion between mL, mg, and "units"
  • • Multi-dose vials with varying concentrations
  • • Patients unfamiliar with drawing from a vial

If you choose a compounded injectable, do not "figure it out yourself." Ask the prescriber or pharmacy to show you exactly how to measure your dose.

3) Shipping and storage problems are a real issue

FDA has received complaints that certain compounded GLP-1 drugs arrived warm or with inadequate ice packs. FDA recommends not using any injectable GLP-1 drug that arrives warm or with insufficient refrigeration, because quality can be affected.

4) Fraud is real (fake labels, fake pharmacies)

FDA reports fraudulent compounded semaglutide/tirzepatide products marketed in the U.S. with false label information. In some cases, the pharmacies listed on labels didn't exist, or the real pharmacy name was used even though it didn't compound the product.

5) Salt forms are a big red flag

FDA warns that some compounded semaglutide products may use salt forms (including semaglutide sodium and semaglutide acetate). FDA states these salt forms are different active ingredients than the base form used in approved drugs, and FDA is not aware of any lawful basis for their use in compounding.

6) Shortage policy changed (why availability can shift)

FDA determined the semaglutide injection shortage was resolved and published timelines around enforcement discretion for compounders. Practical takeaway: compounded availability may change depending on FDA policy, supply conditions, and how each provider structures prescriptions. If you start compounded, have a backup plan.

Safe Buyer Checklist (Use This Before Paying)
  • Prescription + clinician review is required (not "add to cart")
  • The provider will tell you which pharmacy fulfills your prescription
  • The medication is shipped cold-chain when required and arrives properly refrigerated
  • Clear dosing instructions (mg/mL/units are explained)
  • No mention of semaglutide sodium/acetate as the "active ingredient"
  • Clear cancellation/refund rules in writing

How We Verified Pricing (So You Can Trust This)

We don't rank "starting at" prices without context. On January 9, 2026 we:

  • Checked official manufacturer cash-pay pages for Wegovy tablets and Zepbound vials
  • Checked each provider's public pricing/offer page listed in Sources below
  • Flagged plans that require prepay or long-term billing commitments
  • Labeled anything not clearly published as "verify at checkout"

Not guaranteed: Prices and availability can change. For any option you choose, confirm the final all-in total at checkout before paying.

How We Define "Cheapest" (So You Don't Get Tricked)

Most "cheapest GLP-1" pages quietly use one definition (usually "lowest first month price") because it makes their offer look best. In real life, "cheapest" means three different things:

Cheapest FDA-approved

Least regulatory uncertainty

Cheapest FDA injection

What most think of as "the shot"

Cheapest all-in program

"Pay monthly, ship to my door" telehealth

This guide gives you all three—so you can pick what actually fits.

Two Paths: FDA-Approved vs Compounded

Path A: FDA-Approved GLP-1s (Cleanest for Safety/Regulatory Clarity)

FDA-approved usually means:

  • Standardized manufacturing
  • Known dosing formats
  • Published warnings/contraindications
  • Clearer supply chain

2026 changed the game for self-pay: Wegovy tablets and Zepbound vials now have clearly published cash-pay routes.

Time-sensitive: Wegovy's 4 mg tablet self-pay offer is $149 through April 15, 2026, then $199/mo for that dose tier (per official savings page). That's not a "lock-in," but it is a published schedule you can use when deciding when to start.

Path B: Compounded GLP-1 Programs (Often Cheaper, But You Must Vet Them)

Compounded programs can be more affordable, but you trade:

  • FDA premarket review of the finished product
  • Standardized dosing devices (pens) for vials/syringes
  • Consistent manufacturing for more variability

This doesn't mean "never use compounded." It means choose carefully and follow dosing instructions exactly.

Best Compounded Online Programs (Ranked)

#1Tuyo HealthBEST VALUE$155/mo
  • Semaglutide starts at $155/mo (as stated)
  • No membership fees shown (as stated)
  • Lab work every 3 months included (as stated)
Start at $155/mo with labs included
#2Breeze MedsAll 50 StatesStarting at $199
  • FSA/HSA eligible
  • Services all 50 states (per FAQ)
  • Straightforward pricing
Start at $199/mo with Breeze Meds
#3Eden HealthSupport + CoachingFrom $119 first mo*
  • From $119 first month* (*3-month plan discount)
  • Ongoing cost varies by plan—confirm at checkout
  • Free expedited shipping, coaching/community
See Eden pricing
#4SkinnyRxBest for BeginnersFrom $199/mo
  • Comprehensive onboarding process
  • Educational resources included
  • Patient support team
See SkinnyRx pricing
#5MEDViLow Entry$179 first month
  • $179 first month, $299/mo refills (locked in)
  • Includes physician review + plan + 1:1 guidance
  • No contract
Try month 1 for $179
Screenshot Checklist: What to Save Before You Pay

Before checkout, screenshot these items on your provider's page. If something goes wrong later, you'll have proof of what was promised:

  • Monthly price for YOUR dose (not just "starting at")
  • What's included: meds, shipping, labs, supplies?
  • Refund/cancellation policy (before you're charged)
  • Pharmacy name and license (state-licensed 503A or 503B)
  • Provider credentials (licensed physician or NP)
  • Shipping timeline (how fast will it arrive?)

Provider Deep Dives: What You Actually Get

BEST VALUETuyo Health — $155/mo

Why we highlight it:

Tuyo's page is unusually explicit about what's included (no membership fee shown, shipping included, and lab work every 3 months). It's the lowest published starting price we've verified with labs included—a rarity at this price point.

What you get (as stated on their page):

  • Compounded semaglutide starts at $155/month
  • No membership fees
  • Free medical consultation and clinical support
  • Free shipping
  • Lab work every 3 months included

Best for:

Someone who wants the lowest monthly cost for a medically supervised program and wants to avoid surprise add-ons.

What to confirm during intake:

  • • Your exact monthly price at your prescribed dose (pricing varies by dose)
  • • State availability for your location
  • • What happens if you're not approved
Start at $155/mo with labs included
All 50 StatesBreeze Meds — Starting at $199/mo

Why people choose it:

Breeze emphasizes simplicity: starting at $199/mo, FSA/HSA eligible, and their FAQ states they service all 50 states. If you want something straightforward and fast, this is a solid "default" program.

What their site states:

  • • Starting at $199 for weight loss injections
  • • FSA/HSA eligible
  • • "We service all 50 states" (per FAQ)

Best for:

Someone who wants a no-frills, easy online process and broad state availability.

What to confirm during intake:

  • • Dose-based pricing changes (some programs adjust at higher doses)
  • • What's included in the base price (supplies, follow-ups, etc.)
Start at $199/mo with Breeze Meds
BeginnersSkinnyRx — From $199/mo

Why people choose it:

SkinnyRx specializes in first-time GLP-1 users with comprehensive onboarding and educational resources. Ideal if you're new to weight loss medications and want extra guidance.

What SkinnyRx offers:

  • • Comprehensive onboarding process
  • • Educational resources included
  • • Patient support team
  • • Both semaglutide and tirzepatide available

Best for:

First-time GLP-1 users who want thorough education and support throughout their journey.

What to confirm during intake:

  • • Your exact monthly price at your prescribed dose
  • • What's included in the base price
  • • Cancellation and refund terms
See SkinnyRx pricing
Low EntryMEDVi — $179 First Month

Why people choose it:

MEDVi offers one of the lowest first-month prices for injectable semaglutide programs. The $179 entry point can be appealing if you want to try the treatment without a large upfront commitment.

What MEDVi's FAQ states:

  • • First month: $179 (MEDVi Semaglutide program)
  • • Refills: $299/month (listed as "locked in")
  • • Includes: physician review, full personalized plan, 1:1 guidance, prescription medication shipped
  • • Refills include the same program benefits; no contract

Best for:

"I want a very low-cost first month for injectable semaglutide and I'm OK paying more if I continue."

Watch-outs:

The ongoing price ($299/mo) is higher than flat-rate options. If your priority is the lowest long-term monthly cost, compare with Tuyo ($155/mo) or Breeze ($199/mo) first.

Try month 1 for $179
SupportEden — From $119 First Month*

Why people choose it:

Eden isn't the cheapest ongoing price, but it bundles more "clinic feel" support and highlights no membership fees, free expedited shipping, coaching, and consistent pricing across doses (per their page).

What Eden's pricing page states:

  • • From $119 first month* (*first-month discount on 3-month plan)
  • • Ongoing cost varies by plan—confirm your exact total at checkout
  • • No membership fees
  • • Free expedited shipping
  • • Doctor-led plans, coaching and active community
  • • Cancellation: no cancellation fees or long-term contracts (contact support)

Best for:

Someone who wants more guidance and support instead of a bare-minimum program.

What to confirm during intake:

  • • Your refill schedule and timing
  • • Cancellation timing (how close to billing date you must cancel)
See Eden pricing

The Decision Framework (So You Stop Second-Guessing)

1Do you need FDA-approved (not compounded)?

Yes → Start with Wegovy tablets or Zepbound vials.

No → Go to Step 2.

2What's your real budget at Month 6?
  • Under $170/mo: Tuyo ($155/mo)
  • $179–$199/mo: MEDVi ($179 first), Breeze ($199)
  • $200–$300/mo: MEDVi ($299 ongoing), Eden (varies by plan), SkinnyRx (from $199)
3What level of support do you want?
  • Labs included (explicit): Tuyo (every 3 months)
  • Coaching bundled: Eden
  • No-frills / simple price: Breeze
  • Lowest first month: MEDVi ($179)

The Real Cost: What a Year Actually Looks Like

Marketing focuses on Month 1. Smart shoppers budget Month 6 and Month 12.

ProgramExample MonthlyYear 1 Total
Tuyo Health (compounded)BEST VALUE$155/mo~$1,860
Breeze Meds (compounded)$199/mo$2,388
SkinnyRx (compounded)From $199/moFrom $2,388
MEDVi (compounded)$179 + ($299 × 11)$3,468
Eden Health (compounded)See plan pricing*Varies*
Wegovy tablets (FDA-approved)$149/mo$1,788*
Zepbound vials (FDA-approved)$299/mo$3,588*

*Most people titrate up or switch dose tiers over time, so actual totals can be higher.

How to Spot Scams (And Avoid Dangerous Compounded GLP-1)

Green Flags
  • Requires prescription + clinician review
  • Transparent pricing before payment
  • Clear medication type (FDA-approved vs compounded)
  • Clear policies + support channels
Red Flags
  • No prescription required
  • Overseas sourcing
  • "Too good to be true" pricing with no explanation
  • Mentions semaglutide sodium/acetate as equivalent

How to Get GLP-1 Online (The Legit Process)

1. Intake

Medical history

2. Clinician Review

Async or video

3. Prescription

If approved

4. Fulfillment

+ Follow-ups

If a site skips clinician review, it's not a legitimate GLP-1 prescribing workflow.

Side Effects & Safety (Quick, Label-Based Summary)

GLP-1 medications can be highly effective, but they're real prescription drugs with real contraindications and risks. Always review the full prescribing information and talk with a licensed clinician.

Who Should NOT Use These Medications (High-Level)

Both semaglutide (Wegovy) and tirzepatide (Zepbound) carry a boxed warning about thyroid C-cell tumors, and are contraindicated if you (or your family) have a history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). They are also contraindicated in patients with serious hypersensitivity to the active ingredient or excipients.

Wegovy (semaglutide) Common Side Effects

Examples from prescribing information: nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, and others.

Zepbound (tirzepatide) Common Side Effects

Examples from prescribing information: nausea, diarrhea, vomiting, constipation, abdominal pain, dyspepsia, injection site reactions, fatigue, and others.

Serious Side Effects to Know About (Not Exhaustive)

Prescribing information includes warnings/precautions about issues such as:

  • • Pancreatitis
  • • Gallbladder disease
  • • Hypoglycemia risk (especially with insulin/sulfonylureas)
  • • Kidney injury due to volume depletion
  • • Severe GI adverse reactions
  • • Not recommended in severe gastroparesis
  • • Suicidal behavior/ideation monitoring
  • • Aspiration risk during anesthesia

If you have severe symptoms (e.g., severe abdominal pain that won't go away, signs of allergic reaction, or severe dehydration), seek medical help promptly.

Extra Caution for Compounded Injectables

FDA has published safety communications about dosing errors (including hospitalizations) with compounded injectable semaglutide products—often caused by confusion measuring doses from multi-dose vials. If you choose compounded injectables, ask your prescriber or pharmacy to demonstrate dosing clearly before you inject.

Frequently Asked Questions

What is the cheapest GLP-1 without insurance in 2026?

As of January 2026, the cheapest options depend on whether you want FDA-approved or compounded. Wegovy tablets list self-pay pricing from $149/month for starter tiers, Zepbound vials list self-pay pricing from $299/month for starter tiers, and some compounded online programs publish starting prices around $155–$199/month depending on plan structure.

What's the cheapest GLP-1 option under $200/month?

Verified January 2026 pricing shows Wegovy tablets listed at $149/month for certain starter tiers and some compounded programs listing prices between $155 and $199/month, depending on eligibility and plan structure.

Is compounded semaglutide the same as Wegovy or Ozempic?

Compounded semaglutide products are not FDA-approved as finished drugs. The FDA has published concerns about dosing errors with compounded injectable semaglutide and notes compounded drugs do not undergo FDA premarket review for safety, effectiveness, or quality.

What should I avoid when looking for cheap GLP-1 online?

Avoid sites that don't require a prescription, overseas sellers, impossibly low pricing, and any product described as semaglutide sodium or semaglutide acetate as equivalent to approved semaglutide. The FDA notes salt forms are different active ingredients than the base form used in approved drugs.

Does Breeze Meds serve all 50 states?

Breeze Meds' own FAQ states they service all 50 states.

Is the $149 Wegovy pill price a 'lock-in' or just per fill?

It's not a 'lock-in.' Wegovy's official savings page shows the $149 self-pay price for certain dose tiers (1.5 mg and 4 mg through April 15, 2026). Pricing and eligibility rules can change—always confirm the current offer terms before you pay.

What does "refill within 45 days" mean for Zepbound vials?

Zepbound's cash-pay vial pricing ($299–$449/mo depending on dose) requires you to refill within 45 days of your previous delivery/receipt date. If you refill after 45 days, higher 'regular price' tiers apply. Budget for your actual refill cadence.

Are compounded GLP-1s FDA-approved?

No. Compounded drugs do not undergo FDA premarket review as finished products. The FDA notes compounded drugs generally should be used only when a patient's medical needs can't be met by an FDA-approved drug.

What are "semaglutide salt forms" and why avoid them?

FDA warns that some compounded semaglutide products may use salt forms (including semaglutide sodium and semaglutide acetate). FDA states these salt forms are different active ingredients than the base form used in approved drugs, and FDA is not aware of any lawful basis for their use in compounding.

How do I verify a compounding pharmacy?

Ask the provider which pharmacy fulfills your prescription. Check that the pharmacy is licensed in your state. Confirm the medication is shipped cold-chain when required and arrives properly refrigerated. Verify clear dosing instructions are provided.

What's the cheapest option under $200/month that's not prepay?

Among compounded programs that don't require prepay, Tuyo lists $155/mo and Breeze lists $199/mo as monthly recurring pricing. For FDA-approved, Wegovy tablets list $149/mo starter tiers. Always verify current pricing at checkout.

How fast can I typically start?

Timeline varies by provider. Most telehealth programs can complete intake + clinician review within 24–72 hours if you're a good candidate. Medication shipping times vary from 2–7 days depending on the provider and your location.

Bottom Line (What We'd Actually Do)

Start with FDA-approved cash-pay if you want maximum clarity:

  • • Wegovy tablets (starter pricing; note the April 15 change on 4 mg)
  • • Zepbound vials (starter pricing; note the 45-day refill condition)

If you're comfortable with compounded programs (and you vet them):

  • • Tuyo $155/mo (as stated)
  • • MEDVi $179 first month (then $299/mo)
  • • Breeze starting at $199 (as stated; "all 50 states" per FAQ)
  • • Eden from $119 first month* (*3-month plan discount; confirm your total at checkout)

Sources