Yucca Health GLP-1 Cost: What You’ll Really Pay in 2026
By Weight Loss Provider Guide Editorial Team · Last verified: · Next review: June 22, 2026 · This page contains affiliate links. We may earn a commission if you sign up through them. Our recommendations are based on verified pricing, policies, and fit — not commission size.
Bottom line up front: Yucca Health’s lowest published price is $146/month for compounded semaglutide and $258/month for compounded tirzepatide, both as new-patient promotional pricing on the 6-month plan. Your exact quote is shown after intake. Yucca does not take insurance, but HSA/FSA cards work at checkout and Klarna, Affirm, and Afterpay are available on longer plans. The medications are compounded by licensed U.S. pharmacies and are not FDA-approved. This page gives you the full pricing matrix, the billing catches, and a screenshot checklist — so Yucca’s checkout doesn’t surprise you.
This page compares cost and access. A licensed clinician — not us — should decide whether GLP-1 treatment is appropriate for your situation.
First-screen fast answer
| Question | Fast answer |
|---|---|
| Cheapest published semaglutide price | $146/month (new-patient promo, 6-month plan) |
| Cheapest published tirzepatide price | $258/month (new-patient promo, 6-month plan) |
| Exact price shown | After intake, before payment authorization |
| Charged before approval? | No — temporary card hold; charged only if a licensed provider approves treatment |
| Insurance accepted? | No |
| HSA/FSA accepted? | Yes, at checkout — but Yucca does not issue itemized receipts or letters of medical necessity |
| Shipping | Free expedited shipping via UPS 2-Day Air; ships 2–3 business days after approval |
| Availability | Licensed providers in all 50 states; ships within the U.S. |
| Medication type | Compounded — not FDA-approved |
| Best fit | Self-pay shoppers who want async review, BNPL, fast shipping |
| Not a fit | Insurance billing, FDA-approved brand-name medication, labs, live video visits |
How much does Yucca Health GLP-1 cost in 2026?
Yucca Health GLP-1 cost runs from as low as $146/month for compounded semaglutide on the 6-month plan to $385/month for compounded tirzepatide on the monthly plan. The price depends on which medication you choose, which plan length you pick, and whether you qualify for the current new-patient promotion.
The $146 and $258 floors are pulled directly from Yucca’s public pricing pages. The ongoing-month rates are cross-checked against multiple independent reviewer sources and align with Yucca’s published 6-month comparison pricing. Verify your exact quote at checkout before you commit.
The Yucca Health pricing matrix (May 2026)
| Medication | Plan | New-patient mo 1 | Ongoing months | Avg/mo (full plan) | Total over plan | Per week |
|---|---|---|---|---|---|---|
| Semaglutide+ | 1-month | $275 | n/a | $275 | $275 | ~$69 |
| Semaglutide+ | 3-month | $175 | $255 × 2 | ~$228 | ~$685 | ~$57 |
| Semaglutide+ | 6-month ★ Best value | $146 | $206 × 5 | ~$196 | ~$1,176 | ~$49 |
| Tirzepatide+ | 1-month | $385 | n/a | $385 | $385 | ~$96 |
| Tirzepatide+ | 3-month | $258 | $355 × 2 | ~$323 | ~$968 | ~$81 |
| Tirzepatide+ | 6-month ★ Best value | $258 | $325 × 5 | ~$314 | ~$1,883 | ~$78 |
Math assumes Yucca’s current new-patient promo applies to month 1 and the standard plan rate applies to subsequent months. Per-week assumes 4 weekly injections per month. Yucca’s checkout shows your exact first-month and ongoing prices before payment — confirm both before authorizing.
How much does Yucca Health semaglutide cost?
Yucca Health Semaglutide+ costs $146/month for new patients on the 6-month plan as the current promo floor, with $206/month listed as the non-promo 6-month plan rate. The 3-month plan runs approximately $175 first month and $255/month after, and the monthly plan is $275/month. Verify your specific quote at intake.
Semaglutide is the same drug class as Wegovy® and Ozempic®, but Yucca’s version is compounded (mixed by a licensed U.S. pharmacy) and is not FDA-approved. The “+” in “Semaglutide+” means Yucca adds vitamin B12 to the formulation. The added B12 has not been clinically established as essential alongside semaglutide — ask your provider about the formulation before you start.
Real 6-month math at published rates:
- Month 1: $146
- Months 2–6: $206 × 5 = $1,030
- Total over 6 months: ~$1,176
- Effective average: ~$196/month (~$49/week · ~$1.75/day)
For context: brand-name Wegovy®’s list price has historically been ~$1,349/month. NovoCare now offers lower self-pay pricing for eligible patients — verify current NovoCare prices before comparing.
How much does Yucca Health tirzepatide cost?
Yucca Health Tirzepatide+ costs $258/month for new patients on the 6-month plan as the current promo floor, with $325/month listed as the non-promo 6-month rate. The 3-month plan runs ~$258 first month and ~$355/month after, and the monthly plan is ~$385/month. Verify your specific quote at intake.
Tirzepatide is a dual GIP/GLP-1 receptor agonist — the same drug class as FDA-approved Zepbound® and Mounjaro®. Yucca’s Tirzepatide+ is compounded and is not FDA-approved. The “+” again means added B12 in the formulation.
Real 6-month math at published rates:
- Month 1: $258
- Months 2–6: $325 × 5 = $1,625
- Total over 6 months: ~$1,883
- Effective average: ~$314/month (~$78/week)
Brand-name Zepbound® list price runs significantly higher without insurance. Lilly now publishes lower cash-pay pricing starting around $299/month for eligible patients via LillyDirect — verify current Lilly self-pay pricing before comparing.
What’s actually included in the price — and what isn’t
✅ What’s included
- The medication — compounded semaglutide+ or tirzepatide+ with B12, filled by a licensed U.S. pharmacy
- Free expedited shipping — UPS 2-Day Air or equivalent, $0 at checkout
- Provider review — licensed U.S. provider, typically within 24 hours
- Dose adjustments — provider can adjust over time within your active plan
- 24/7 support — live human support via portal messaging
- Patient portal — records, refill schedule, and provider messaging
- Injection kit (needles, syringes, alcohol wipes) — confirm at checkout
❌ What’s not included
- Insurance billing — Yucca does not bill any insurance. Period.
- Itemized receipts or letters of medical necessity — HSA/FSA cards work, but Yucca doesn’t issue required documentation
- FDA-approved brand-name medication — Yucca is compounded only
- Live video visits — Yucca is async only
- Lab work — Yucca says most patients complete the process entirely online
- Refunds on shipped medication — final sale once shipped
Need FDA-approved brand-name medication?
Ro carries Wegovy®, Zepbound®, and Foundayo™ with insurance support and prior-auth concierge.
The honest catch: 4 things that can change your cost after you sign up
Yucca Health is a legitimate provider — that’s not the question. The question is whether you’ll be surprised after checkout. Four things commonly catch new patients off guard. None are hidden. All are in Yucca’s published policies. They’re just easy to miss.
Yucca's own FAQ says: "Renewals are processed 5–7 days early to ensure timely fulfillment and delivery." This is so your next shipment arrives before you run out. It also means if you expect the charge on day 30, it can hit on day 23–25.
The "$146/month" you see in the ad is the new-patient first-month price on the 6-month plan. Yucca publicly lists $206/month as the non-promo 6-month semaglutide price. Multiple independent reviewer sources and customer reviews report that first-month and ongoing prices differ — months 2 through 6 on the 6-month plan likely run at the higher published rate. This is not a bait-and-switch. It's how the promo is structured. But the jump from $146 to $206 catches people who only read the headline.
Yucca's published refund policy is direct: "Refunds are only available in cases of billing errors, duplicate charges, or if a provider does not approve your treatment." If the medication makes you sick, the bottle is already shipped, and you decide to stop after week one — that's still your money. Compounded medications are made specifically for you, which is why they can't be returned.
Yucca says you can cancel an order that hasn't been processed yet through your patient portal. Once the pharmacy starts compounding for that month, cancellation is not guaranteed.
So is Yucca worth it despite this?
Honest answer: yes, for the right person. Yucca Health is not the cheapest first-month sticker in the compounded GLP-1 market. But because Yucca isn’t chasing the lowest possible price, they can include free expedited shipping on every plan, asynchronous provider review with no live visit required, a 4.6/5 average across over 1,090 Trustpilot reviews, and 24/7 human support — none of which the deep-discount providers consistently match. If your priority is the lowest first-month sticker, you have better options. If your priority is a strong-service compounded GLP-1 provider with a transparent published price floor, Yucca is one of the strongest options in the category.
Need the lowest possible compounded floor regardless of service? See our cheapest compounded semaglutide comparison →
Will Yucca charge me monthly, quarterly, or for the full 6-month plan?
What we know from Yucca’s public pages
- Temporary hold at intake — only charged after provider approval
- 6-month prescription auto-renews until the term ends
- Within that term, payments may be monthly, quarterly, or another schedule shown at checkout
- Renewals process 5–7 days early to ensure timely fulfillment
Screenshot these at checkout
- Dollar amount being charged today
- Dollar amount of your next charge (and when it will hit)
- Whether subsequent charges are monthly, quarterly, or 6-month
- Your renewal date and the date 7 days before it
Yucca Health cost vs. other GLP-1 providers (2026)
Yucca Health sits in the mid-tier of compounded GLP-1 pricing — not the cheapest, not the most expensive. Where Yucca wins is service-and-price together: a strong published floor with free expedited shipping, async review, BNPL options, and high review volume.
| Provider | Compounded sema entry | Compounded tirz entry | Medication path | Best for |
|---|---|---|---|---|
| Yucca Health | $146/mo new-patient (6-mo plan) | $258/mo new-patient (6-mo plan) | Compounded + B12 | Self-pay, async, fast-shipping, BNPL |
| MEDVi | from $179/mo intro | varies — verify at intake | Compounded, deep menu (oral + injection) | Broad cash-pay shoppers comparing options |
| Eden | Varies — verify at intake | Varies — verify at intake | Compounded + FDA-approved branded options | Mainstream self-pay with branded path |
| Ro | Not applicable | Not applicable | FDA-approved Wegovy®, Zepbound®, Foundayo™ | Insurance, brand-name, prior-auth help |
| LillyDirect (cash) | Not applicable | $299–$449/mo FDA-approved Zepbound® vials/KwikPens | FDA-approved cash-pay direct from manufacturer | Brand-name vial users without telehealth |
Ro’s program fee is $39 for the first month, then $149/month ongoing, or as low as $74/month with annual prepay — medication billed separately at Ro’s published cash-pay rates. Verify all competitor pricing at the provider’s checkout before comparing.
Pick the path that matches your real problem
| If your problem is… | Yucca answer | Better alternative |
|---|---|---|
| Need insurance billing | Yucca does not accept insurance | Ro — insurance concierge + free coverage checker |
| Need FDA-approved weight-loss medication | Yucca is compounded only | Ro — Wegovy®, Zepbound®, Foundayo™ |
| Need live video visits | Yucca is async only | Sesame Care |
| Need labs before starting | Yucca doesn't require or include labs | Enhance MD |
| Need HSA/FSA documentation | Yucca doesn't issue itemized receipts or LMNs | See HSA/FSA-friendly providers → |
| Need cheapest first-month sticker | Yucca isn't the cheapest entry price | See cheapest compounded semaglutide → |
| Want broadest compounded menu (oral + injection) | Yucca is injection-only | MEDVi |
| Genuinely unsure | — | Take the 60-second matching quiz → |
Payment plans: how Klarna, Affirm, and Afterpay work on Yucca Health
Yucca Health offers Klarna, Affirm, and Afterpay at checkout on longer plans. Specific terms — installment counts, interest, credit-check type, and approval — are set by the BNPL provider at checkout, not by Yucca. None of these make the medication itself cheaper. They spread the payment timing.
Roughly how this looks in practice:
- Semaglutide+ 6-month plan (~$206 ongoing/month) → 4-installment Klarna split ≈ $51 per installment
- Tirzepatide+ 6-month plan (~$325/month) → 4-installment Klarna split ≈ $81 per installment
- Klarna or Afterpay: Typically the simplest split — often 4 payments over ~6 weeks, interest-free if paid on schedule. Best for the cleanest short-term spread.
- Affirm: Can offer longer plans (6 or 12 months). Useful if you want more time, but check the interest rate before accepting.
- Honest truth: BNPL does not lower your total cost. It moves the timing. Use it if you want lower per-paycheck pressure — not because it makes Yucca cheaper.
Does Yucca Health take insurance, HSA, or FSA?
If you have insurance that might cover GLP-1s → Ro
Ro is the primary option in 2026 for commercial insurance coverage on Wegovy®, Zepbound®, or Foundayo™. They offer a free GLP-1 Insurance Coverage Checker, dedicated insurance concierge for prior-authorization paperwork, and Ro Body membership starting at $39 for the first month.
Check Ro’s insurance coverage tool →If you want to use HSA/FSA dollars
Your HSA/FSA administrator decides what’s reimbursable. Many plans require an itemized receipt with the medication name, prescribing provider, and an explicit medical purpose — plus a Letter of Medical Necessity for weight management. Yucca does not provide these documents. Call your plan administrator before you commit if HSA/FSA reimbursement is essential to your decision.
Is Yucca Health FDA-approved?
FDA-approved weight-loss medications (on-label)
- Wegovy® — semaglutide, FDA-approved for chronic weight management
- Zepbound® — tirzepatide, FDA-approved for chronic weight management
- Foundayo™ — orforglipron, oral FDA-approved (approved April 1, 2026)
What “compounded” means
A compounding pharmacy mixes medications for individual patients based on a provider’s prescription. Compounded GLP-1s are governed by state pharmacy boards and federal compounding rules (sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act) — not by FDA’s drug-approval process.
A compounded path may be worth discussing if:
- You’re paying cash and the cost difference matters
- You understand compounded medication is not FDA-reviewed
- You’re working with a licensed U.S. pharmacy
A compounded path is probably not for you if:
- You specifically want FDA-approved weight-loss medication
- Insurance coverage of FDA-approved medication is realistic for you
- You’re uncomfortable with the regulatory distinction
- You have complex medical history that warrants more oversight
Questions to ask your provider before starting anything:
- What exactly is being prescribed? Is it compounded or FDA-approved brand-name?
- Which pharmacy is filling it?
- What’s the dose schedule?
- What side effects should I expect and what should trigger a call?
- What conditions in my history matter (thyroid history, pancreatitis, gallbladder, kidney function, mental health, pregnancy)?
- What’s the plan if I can’t tolerate the side effects?
If you fall into the “want FDA-approved medication” camp: Compare Ro vs Yucca Health →
See Ro →Who Yucca Health is best for — and who should skip it
✅ Yucca Health is a fit if you…
- Are paying cash and want a strong published price floor
- Want async provider review (no live video visit required)
- Want approval-first billing — charged only after approval
- Want free expedited shipping included
- Want the option to pay in installments via BNPL
- Are comfortable with compounded medication
- Are willing to commit to at least 3 months for a lower per-month rate
- Are okay with the “shipped is final” refund policy
❌ Yucca Health is not a fit if you…
- Need insurance billing or prior-auth help → Try Ro
- Want FDA-approved Wegovy®, Zepbound®, Foundayo™ → Try Ro
- Need itemized HSA/FSA receipts or a LMN → See HSA/FSA providers
- Want a live video visit → Try Sesame Care
- Want lab work included → Try Enhance MD
- Want month-to-month flexibility at a lower per-month rate
- Are not comfortable with compounded medication
- Need the lowest possible compounded floor → See cheapest options
| Your priority | Best path |
|---|---|
| Strong-service compounded semaglutide at a transparent floor | Yucca Health 6-month plan |
| Strong-service compounded tirzepatide at a transparent floor | Yucca Health 6-month plan |
| Absolute lowest first-month sticker price | See our cheapest-compounded comparison |
| FDA-approved Wegovy®, Zepbound®, Foundayo™ | Ro |
| Insurance coverage check + prior-auth help | Ro |
| Provider choice + video visits + brand-name | Sesame Care |
| Broadest compounded menu (oral + injection) | MEDVi |
| Premium clinical feel with labs | Enhance MD |
| Genuinely unsure | Take the 60-second matching quiz |
How to sign up for Yucca Health, step by step
Yucca’s sign-up is a quick online intake plus up to 24 hours for provider review. Total time from “I’m interested” to “medication at my door” is typically 3–5 business days.
- 1Take the eligibility intake — on tryyucca.com — short medical history questions
- 2Verify your identity — upload a photo of your driver's license
- 3Choose your treatment — Semaglutide+ or Tirzepatide+
- 4Choose your plan length — 1-month, 3-month, or 6-month
- 5Authorize payment — Yucca holds your card; nothing is charged yet
- 6Provider reviews your intake — typically within 24 hours; if approved, card is charged and pharmacy starts compounding
- 7Medication ships — 2–3 business days after approval via UPS 2-Day Air (Mon–Fri only; no weekend shipping)
Eligibility basics
- BMI 30 or higher, or
- BMI 27 or higher with a weight-related condition (type 2 diabetes, high blood pressure, high cholesterol, sleep apnea, or cardiovascular disease)
- BMI above 25 may also qualify depending on medical history
- 18 or older · Lives in the United States
A licensed provider has final say. Yucca doesn’t guarantee approval.
The 7 things to screenshot before you authorize payment
Don’t sign up for any telehealth subscription without writing the terms down. Before you click “Authorize Payment” on Yucca’s checkout, screenshot these seven things. It takes about 90 seconds and saves you every “wait, what was I quoted?” headache later.
- The medication name and formulation. Semaglutide+ or Tirzepatide+. Note that B12 is in the formulation.
- The plan length you selected. 1-month, 3-month, or 6-month.
- The amount being charged today. This should match the new-patient promo if you’re a new patient.
- The ongoing monthly amount. This is what hits your card from month 2 onward.
- The billing cadence and renewal date. Whether you’ll be charged monthly, quarterly, or otherwise. Note both the renewal date and the date 7 days before (when the early charge may hit).
- The cancellation cutoff and how to cancel. Through the portal in writing. Yucca says orders not yet processed by the pharmacy can be canceled; once the pharmacy starts, it’s not guaranteed.
- The refund policy text. Specifically: “Refunds are only available in cases of billing errors, duplicate charges, or if a provider does not approve your treatment.”
Save these to a folder titled “Yucca Health start [date].” If anything goes wrong later, you have the receipts.
What real Yucca Health customers say
Three representative customer experiences from Yucca’s public Trustpilot profile (over 1,090 reviews at a 4.6/5 average as of May 22, 2026). Two positive, one critical — picked for balance.
“Excellent customer service, and they answered all my questions and concerns. Received my order for the first three months. I’m very excited to start tomorrow.”
“I am new to Yucca Health, but so far the customer care, their website and their customer representatives have been amazing.”
“I signed up for six months at $146 and on my second package this company charged my credit card $275.”
The critical review reflects the exact friction we covered in the “honest catch” section — the gap between the first-month promo and the ongoing monthly rate. Yucca responded publicly on Trustpilot saying the team would reach out to clarify the account. The pattern is real, it’s addressable if you screenshot your terms at checkout, and it’s why we wrote the 7-point screenshot checklist above. Individual experiences vary. These testimonials reflect service experience and billing, not medical results.
How we verified this pricing
Every Yucca Health price on this page was checked against tryyucca.com on May 22, 2026. Public floor prices and policy claims come directly from Yucca’s own pages. Ongoing-month rates come from multiple independent reviewer sources cross-checked against Yucca’s public 6-month comparison pricing. Your specific quote is finalized inside Yucca’s intake flow. Last verified: · Next scheduled re-verification: June 22, 2026.
| Claim | Source level |
|---|---|
| Semaglutide+ public starting price ($146 new patient, 6-mo plan) | ✅ Yucca's own pricing page |
| Tirzepatide+ public starting price ($258 new patient, 6-mo plan) | ✅ Yucca's own pricing page |
| Plan length structure (1-mo, 3-mo, 6-mo) | ✅ Yucca's own Explore Treatments page |
| Ongoing-month rates ($206 sema, $325 tirz on 6-mo plan) | ⚠️ Yucca's public 6-mo comparison pricing + secondary reviewer sources; verify your exact quote at intake |
| Renewals process 5–7 days early | ✅ Yucca FAQ |
| Card authorized at intake, charged only after provider approval | ✅ Yucca FAQ |
| Free expedited shipping via UPS 2-Day Air or equivalent | ✅ Yucca Shipping Policy + FAQ |
| Ships Mon–Fri only (cold-chain) | ✅ Yucca FAQ |
| Refund policy text | ✅ Yucca FAQ |
| No insurance accepted | ✅ Yucca FAQ |
| HSA/FSA: cards work, but no itemized receipts or LMN issued | ✅ Yucca FAQ |
| BNPL (Klarna, Affirm, Afterpay) on longer plans | ✅ Yucca FAQ + multiple secondary sources |
| Compounded medication, not FDA-approved | ✅ Yucca FAQ + Terms of Service |
| Licensed providers in all 50 states; ships within the U.S. | ✅ Yucca FAQ |
| Trustpilot rating (4.6/5, ~1,090 reviews) | ✅ Trustpilot.com |
| Whether dose increases change price | ❓ Not published; verify at intake |
| Which specific pharmacy fills any individual prescription | ❓ Not published; verify at intake |
We do not rank GLP-1 providers by price alone. We weigh verified pricing, what’s included, plan friction, cancel/refund risk, insurance fit, FDA-approved vs compounded path, support quality, shipping reliability, and how well the provider matches a specific reader’s situation. If a higher-paying affiliate is not the right answer for your situation, we tell you and route you to the better fit.
Yucca Health GLP-1 Cost FAQ
Sources & verification
- Yucca Health FAQ — tryyucca.com/frequently-asked-questions
- Yucca Health Semaglutide+ product page — tryyucca.com/semaglutide
- Yucca Health Tirzepatide+ product page — tryyucca.com/tirzepatide
- Yucca Health Explore Treatments — tryyucca.com/explore-treatments
- Yucca Health Refund Policy — tryyucca.com/refund-policy
- Yucca Health Shipping Policy — tryyucca.com/shipping-policy
- Yucca Health Terms of Service — tryyucca.com/terms-of-service
- Trustpilot — Yucca Health — trustpilot.com/review/tryyucca.com
- FDA — Unapproved GLP-1 drugs used for weight loss — fda.gov
- Ro Weight Loss Pricing — ro.co/weight-loss/pricing/
- NovoCare Wegovy® cost information — novocare.com
- LillyDirect Zepbound® self-pay information — Eli Lilly published pricing
- Independent secondary sources cross-checked: glp1drugs.org, telehealthally.com, glp1clinics.org
Still not sure which GLP-1 program is right for you?
If Yucca Health doesn’t feel like the obvious fit — maybe you want FDA-approved medication, maybe you have insurance, maybe you want more support — don’t guess. Our free 60-second matching quiz recommends a specific provider based on your budget, insurance status, FDA-approved vs compounded preference, and how much support you actually want.
Approval-first billing · Free expedited shipping · Licensed providers in all 50 states
Weight Loss Provider Guide is an independent comparison resource for GLP-1 telehealth providers. We may earn affiliate commissions on sign-ups from this page. Editorial recommendations are not influenced by affiliate payouts. Page last verified . This page is a cost and provider-comparison resource for adults shopping GLP-1 telehealth options. It is not medical advice.