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South Dakota GLP-1 Affordability: 17 Hours of Work for One Month of Medication

A South Dakota worker earning the median wage must work 2.1 full days to afford one month of GLP-1 medication, ranking #10 of 51 nationally.

2026 analysis using BLS wage data and current manufacturer pricing | Updated February 2026

#10
of 51 (50 states + DC) — 1 = least affordable
17
hours/month at
median wage
13.1%
of monthly
take-home pay
115.1%
of a year’s savings
spent on 12 months of Rx
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South Dakota has an obesity rate of 35.2% — 20th highest in the nation — but ranks #10 least affordable out of 51 for the treatment.

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According to the 2026 GLP-1 Affordability Index, South Dakota workers earning median wages must spend 13.1% of their monthly take-home pay — equivalent to 17 hours of work — to afford one month of GLP-1 weight loss medication at the best available self-pay price ($349/mo), ranking the state #10 of 51 nationally.

A year of GLP-1 medication at the current self-pay price ($4,188) consumes 115.1% of what the average South Dakota resident saves annually — meaning South Dakota workers must sacrifice 1.15 years of personal savings for 12 months of treatment.

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vs. National Average: +1.5 hours worse
Neighboring States: North Dakota #32, Minnesota #40, Iowa #19, Nebraska #21
South Dakota Adult Obesity Rate: 35.2% (CDC 2024)
South Dakota Medicaid Covers GLP-1 for Obesity: No (KFF, Jan 2026)
⚠️ South Dakota is a “Double Bind” stateranking in the top 25 for obesity prevalence while ranking in the bottom half for GLP-1 affordability. The people who need this medication most are least able to afford it. Read the full Double Bind analysis →
Detailed Pricing Comparison
MetricSelf-Pay ($349/mo)Wegovy List ($1,349/mo)
Monthly Cost$349$1,349
Annual Cost$4,188$16,188
Hours at Median Wage ($20.49/hr)1765.8
Hours at Minimum Wage ($11.85/hr)29.5113.8
% of Monthly Take-Home Pay13.1%50.6%
Working Days per Month2.18.2
Annual Cost as % of Savings115.1%445%
160-Hour Wall (Min Wage)NoNo
Source: BLS OEWS May 2024, DOL, Novo Nordisk
How South Dakota Compares to Neighboring States
StateMedian WageHours (Self-Pay)RankObesity Rate
South Dakota$20.4917#1035.2%
North Dakota$23.2715#3235.8%
Minnesota$25.1813.9#4030.8%
Iowa$21.4416.3#1937.4%
Nebraska$21.3916.3#2135.2%
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South Dakota GLP-1 Affordability: 17 hours of work per month
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<img src="https://weightlossproviderguide.com/research/images/glp1-statcard-south-dakota.webp" alt="South Dakota GLP-1 Affordability: 17 hours of work per month" width="1200" height="630">
<p>Source: <a href="https://weightlossproviderguide.com/research/glp1-affordability-index/south-dakota/">GLP-1 Affordability Index</a>, 2026</p>
Methodology: How we calculated these numbers

This analysis uses publicly available federal data to measure how affordable GLP-1 weight loss medications are for workers in each U.S. state.

WAGE DATA: Median hourly wages are from the Bureau of Labor Statistics Occupational Employment and Wage Statistics (OEWS) program, May 2024 release. We use the “All Occupations” (SOC 00-0000) median hourly wage for each state. Minimum wages reflect state rates effective January 1, 2026, from the U.S. Department of Labor Wage and Hour Division.

INCOME DATA: Median household income from the U.S. Census Bureau 2024 American Community Survey (ACS) 1-year estimates. Estimated annual savings calculated as median household income × 5.0%, assuming a 5% personal saving rate (illustrative estimate).

MEDICATION PRICING: Self-pay price of $349/month reflects Novo Nordisk self-pay cash pricing via NovoCare Pharmacy (terms apply; government beneficiaries excluded). Wegovy list price of $1,349/month reflects the wholesale acquisition cost (WAC). Both prices current as of February 2026.

NOTE: As of January 2026, an oral Wegovy pill is also available at $149–$299/mo via NovoCare Pharmacy. This analysis uses the Wegovy injectable self-pay price of $349/mo as the baseline.

HEALTH DATA: Adult obesity prevalence from the CDC Behavioral Risk Factor Surveillance System (BRFSS) 2024. Medicaid GLP-1 coverage status from KFF analysis as of January 2026.

CALCULATIONS:

  • Hours of work = Monthly drug cost ÷ hourly wage
  • % of take-home pay = Monthly drug cost ÷ (hourly wage × 173.33 hours/month × 0.75 tax adjustment) × 100
  • 160-Hour Wall = Flagged when hours at minimum wage for list price exceeds 160 (standard full-time month)
  • Double Bind = State has obesity rate ≥ 35% AND affordability rank in bottom half
  • Savings Wipeout = Annual drug cost ÷ estimated annual savings × 100

LIMITATIONS: Take-home pay estimate uses a flat 25% deduction for taxes/FICA, which varies by state and individual circumstances. Savings estimates are approximations. Actual out-of-pocket costs vary based on insurance, employer coverage, and eligibility for manufacturer programs.

Full dataset available for download: CSV Full methodology

Because South Dakota Medicaid does not cover GLP-1s for weight management, many residents are exploring regulated alternatives.

→ Read our 2026 guide: How South Dakota residents are accessing GLP-1 medications

Cite This Page

“GLP-1 Affordability Index: South Dakota.” Weight Loss Provider Guide, 2026.
https://weightlossproviderguide.com/research/glp1-affordability-index/south-dakota/

Data sources: Bureau of Labor Statistics • U.S. Census Bureau • CDC • KFF • Novo Nordisk
Licensed under CC BY 4.0 • Last updated: February 2026
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